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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTN2
All Species:
26.06
Human Site:
Y418
Identified Species:
63.7
UniProt:
P35609
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35609
NP_001094.1
894
103854
Y418
S
T
H
E
T
W
A
Y
G
K
E
Q
I
L
L
Chimpanzee
Pan troglodytes
XP_001158729
890
103312
Y418
S
T
H
E
T
W
A
Y
G
K
E
Q
I
L
L
Rhesus Macaque
Macaca mulatta
XP_001097795
894
103838
Y418
S
T
H
E
T
W
A
Y
G
K
E
Q
I
L
L
Dog
Lupus familis
XP_856116
894
103763
Y418
S
T
H
E
T
W
A
Y
G
K
E
Q
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI91
894
103635
Y418
S
T
H
E
T
W
A
Y
G
K
E
Q
I
L
L
Rat
Rattus norvegicus
Q9Z1P2
892
102942
D411
S
I
H
E
A
W
T
D
G
K
E
A
M
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20111
897
104257
Y421
S
T
H
E
Q
W
A
Y
G
K
E
Q
I
L
L
Frog
Xenopus laevis
NP_001086917
894
103890
A418
S
L
H
E
S
W
T
A
G
K
E
Q
L
L
S
Zebra Danio
Brachydanio rerio
NP_001032662
895
103348
T419
S
N
H
E
S
W
A
T
G
K
E
E
M
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18091
924
107001
R443
D
A
H
E
D
W
T
R
G
K
E
E
M
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
99.7
99.3
N.A.
98.5
79.5
N.A.
N.A.
94.8
87
84.9
N.A.
66.8
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
99.8
99.6
N.A.
98.9
89.4
N.A.
N.A.
97.7
94.1
92.1
N.A.
81.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
N.A.
93.3
60
60
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
N.A.
93.3
73.3
80
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
70
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
0
0
0
0
0
0
100
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
60
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
10
100
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
70
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
90
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
60
0
0
50
0
30
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _